In the autumn of 1995, Miller became one of the very few women to host her own late-night talk show, surprisingly titled as The Stephanie Miller Show, syndicated by Buena Vista Television.
The show was cancelled after thirteen weeks on the air.
She also served as a frequent panelist on PAX-TV's short-lived game show Balderdash, which was hosted by Miller's friend Elayne Boosler.
Miller's radio show was briefly televised live from 6 a.m. Eastern time on MSNBC from April 20 to May 2, 2007.
She also covers a great deal of celebrity news/gossip and off-the-wall stories.
Later that year, she also began co-hosting the CNBC television show Equal Time, as the liberal counterpoint to conservative Bay Buchanan.
a brief apperance as a nurse on General Hospital, and she was in an episode of the TV series Diagnosis: Murder.
Her most significant acting role was in the 1997 comedy film Just Write.
Miller also has special guest co-hosts: Edie Mc Clurg for "Mondays with Mc Clurg", Aisha Tyler for "Tuesdays with Tyler", Hal Sparks on Wednesdays for "Hump Days with Hal" and John Fugelsang for "Fridays with Fugelsang".
She often shares personal details about her life, from something as simple as a household appliance not working to much more intimate details, about sweat, insomnia and even what she calls "shy pee syndrome", which is actually paruresis.
During this period, the show originated from MSNBC's studio in Secaucus, New Jersey, the studios and time slot formerly used by the now-cancelled Imus in the Morning. cities such as Los Angeles, San Francisco, Chicago and Seattle on XM Satellite Radio's America left channel 127.